![]() This can be used to edit text for Wikipedia and any other wiki based on the MediaWiki software application. The current version of Aquamacs includes a Wikipedia mode. They can also choose to bring back GNU Emacs behaviors. ![]() Users can configure Aquamacs with Emacs customization options. These packages are installed without the need of further configuration by the end user.Īquamacs is designed to be highly compatible with Emacs, so that extension packages for GNU Emacs can be installed. Īquamacs is a distribution that includes a number of extensions to GNU Emacs to provide an integrated development environment and to support, among many formalisms, LaTeX, Python, Java, Lisp and Objective C editing, as well as the Emacs Speaks Statistics system for R and S. Visually, Aquamacs has been adapted in its icons and fonts to look similar to other Mac applications. The styles of windows can be automatically changed to suit the major mode used in the buffer shown. A standard printing dialog and functions to efficiently use the Option key on Mac keyboards as Emacs Meta key have been added. ![]() A range of keybindings (keyboard shortcuts) that are standard on macOS, such as Command-W to close a window, or Command-S to save the file, are available. Although GNU Emacs has had native UI support on macOS using the Cocoa API since version 23, Aquamacs modifies the user interface to conform with macOS standards in favor of Emacs standards.Īmong the changes are that Aquamacs, by default, shows tabs to organize different file buffers in windows. It is based on GNU Emacs, currently tracking the GNU Emacs version 25.3 branch. com /davidswelt /aquamacs-emacsĪquamacs is an Emacs text editor for macOS. This assay can quickly and accurately quantify the number of human astrocytes and microglia in mixed cell culture and can be applied to quantifying a range of other cells/objects with complex morphology in neuroscience research. Significant correlations have been consistently achieved between the data obtained from CCC analysis and manual cell counts. The time needed to analyze each image is 1.82 s. The CCC assay consists of four main aspects: image processing with a unique combination of morphology filters digital thresholding integrated morphometry analysis and a configuration of object standards. This method, called the complex cell count (CCC) assay, utilizes a combination of image processing and analysis operations from MetaMorph™ (Version 6.2.6, Molecular Devices). We have developed a fully automated, fast, accurate and objective method for the quantification of primary human GFAP-positive astrocytes and CD45-positive microglia from images of mixed cell populations. However, it has been more difficult to automate the counting of specific cell types with complex morphologies in mixed cell cultures. The ability to diminish apoptosis may contribute to maintaining healthy tissues.Īutomated image-based and biochemical assays have greatly increased throughput for quantifying cell numbers in in vitro studies. Importantly, both cerium oxide and platinum nanoparticles reduce oxidant-mediated apoptosis in target cells as judged by the activation of caspase 3. Furthermore, cerium oxide and platinum nanoparticles demonstrated superoxide dismutase catalytic activity, but did not promote hemolytic or cytolytic pathways in living cells. Using surface plasmon-enhanced microscopy, we find that these nanoparticles associate with cells. Cerium oxide and platinum nanoparticles were found to be 16 ± 2.4 and 1.9 ± 0.2 nm in diameter, respectively. In the present study, we directly compare these two classes of catalytic nanoparticles. Cerium oxide and platinum nanoparticles represent two potentially therapeutic nanoparticles that de-toxify ROS. Several diseases, including many blinding eye diseases, are promoted by excessive oxidant stress due to reactive oxygen species (ROS). High-Content Screening with AgileOptix TechnologyĬatalytic nanoparticles represent a potential clinical approach to replace or correct aberrant enzymatic activities in patients.PROTEIN DETECTION, QUANTITATION, ANALYSIS.NUCLEIC ACID (DNA/RNA) DETECTION & ANALYSIS.SpectraTest Validation Plates and Recertification.GXP SOFTWARE INSTALLATION AND VALIDATION.HIGH-THROUGHPUT, HIGH CONTENT SCREENING.COVID-19 RESPONSE - We are committed to supporting our scientific community during this pandemic.
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